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Dong Quai Side Effects, Interactions and Warnings



  • Dong quai may increase the effects of antidepressants due to the fact that it may alter serotonin levels in the brain.
    -Serotonergic activity-guided phytochemical investigation of the roots of Angelica sinensis. -- Deng S, Chen SN, Yao P, Nikolic D, van Breemen RB, Bolton JL, Fong HH, Farnsworth NR, Pauli GF. -- J Nat Prod. 2006 Apr;69(4):536-41.

  • Since the effects of Dong Quai have not been fully evaluated during pregnany or breastfeeding, it is not recommended. If you experience excessive menstrual flow, stop using the product.
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    - Murray, M. -- The Pill Book Guide to Natural Medicines: Vitamins, Minerals, Nutritional Supplements, Herbs, and Other Natural Products. -- Bantam, 2002. 624-625.

  • Dong quai has been associated with documented reports of potential interactions with warfarin. It is not recommended for people taking blood-thinning agents.
    - Am J Health Syst Pharm 2000 Jul 1;57(13):1221-7; quiz 1228-30 -- Potential interactions between alternative therapies and warfarin. -- Heck AM, DeWitt BA, Lukes AL.








last update: February 2014



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