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Clopidogrel - Interactions and Warnings

Adverse events may include rash, diarrhea, and abnormal liver function.
- Cerebrovasc Dis 1999 Sep-Oct;9(5):253-60 -- Clopidogrel for cerebrovascular prevention. -- Paciaroni M, Bogousslavsky J.

Clopidogrel, an inhibitor of platelet aggregation, was initially thought to be free of the side-effects of ticlopidine. Description of a man who developed aplastic anaemia after 5 months of treatment with clopidogrel. There were no other plausible causes. Suggests that his fatal aplastic anaemia might have been induced by clopidogrel.
- Lancet 2001 Feb 10;357(9254):446 -- Fatal aplastic anaemia associated with clopidogrel.

This drug should not be used if you have a peptic ulcer or a history of brain hemorrhage. Consult your doctor if you have a history of bleeding problems or if you develop bleeding problems while taking this drug. Use of clopidogrel may cause complications in patients with liver disease, since the liver inactivates the drug.

Potentially dangerous interactions can occur with a variety of prescription and non prescription. Consult with your physician before taking any drugs, herbs or supplements.

last update: November 2008

This information is not intended to be a substitute for professional medical advice. You should not use this material to diagnose or treat a health condition or disease without consulting with your healthcare provider.
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