vytorin

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Vytorin - Interactions and Warnings


In a letter to the journal, Neurology, it was claimed/stated that grapefruit juice can increase levels of this drug in the blood. In separate studies, some suggest that pomegranate juice may have the same effect.
- Dreier JP, Endres M. Statin-associated rhabdomyolysis triggered by grapefruit consumption. Neurology 2004;62:670.

Interactions of some of these cholesterol-lowering agents with cyclosporine, erythromycin, high-dose niacin, or gemfibrozil may produce myopathy with or without rhabdomyolysis.
- Am J Health Syst Pharm. 1995 Aug 1;52(15):1639-45. Interactions with hydroxymethylglutaryl-coenzyme A reductase inhibitors.Garnett WR.

Red yeast rice significantly reduces total cholesterol, LDL cholesterol, and total triacylglycerol concentrations. This can cause an adverse interaction with statin drugs.
- Am J Clin Nutr. 1999 Feb;69(2):231-6. Cholesterol-lowering effects of a proprietary Chinese red-yeast-rice dietary supplement.Heber D, Yip I, Ashley JM, Elashoff DA, Elashoff RM, Go VL.

St. John's Wort may interfere with the actions of simvastatin, an ingredient in Vytorin.
- Eggertsen R, Andreasson A, Andren L. Effects of treatment with a commercially available St John's Wort product (Movina) on cholesterol levels in patients with hypercholesterolemia treated with simvastatin. Scand J Prim Health Care 207;25:154–9.

Consult with your physician about whether this drug can interact with other medications that you are taking. Serious interactions can be avoided by staying in contact with your doctor as they may have the most recent data.





last update: May 2009



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