Resources | Health News | Therapies | Fitness


Orfadin®

Brand Name: Orfadin®
Active Ingredient:   nitisinone
Strength(s): 2 mg, 5 mg, and 10 mg
Dosage Form(s):   Capsules
Company Name:    Swedish Orphan International, AB
Availability:         Prescription only
*Date Approved by FDA:   January 18, 2002
*Approval by FDA does not mean that the drug is available for consumers at this time.




What is Orfadin used for? 

Orfadin is used to treat hereditary tyrosinemia type 1, a rare pediatric disease causing progressive liver failure and liver cancer in young children. It is used along with a diet restricting the amino acids tyrosine and phenylalanine. 

Special Warnings with Orfadin:

Patients and their parents or caregivers should tell their doctor right away about: 

  • any unexplained eye symptoms (eye pain, redness, swelling or burning of the eyes) 
  • rash 
  • jaundice (yellowing of the skin and whites of the eyes, and dark color to the urine) 
  • excessive bleeding 

What should I tell my health care provider? 

  • Tell your health care provider if you are trying to become pregnant, are already pregnant, or are breast-feeding. 
  • Tell your health care provider if you are allergic to nitisinone (Orfadin) or to any of the other ingredients in Orfadin. 
  • Tell your health care provider about all the medicines you take, including prescription and non-prescription medicines, vitamins, and herbal supplements

What are some possible side effects of Orfadin? (This is NOT a complete list of side effects reported with Orfadin. Your health care provider can discuss with you a more complete list of side effects.)

The most common side effects of Orfadin were related to high tyrosine levels due to patients not eating the right foods as well as rare cases of a decrease in platelet and white blood cell counts. 

For more detailed information about Orfadin, ask your health care provider or pharmacist.

http://www.fda.gov/cder/foi/label/2002/21232lbl.pdf    Link to Orfadin's Labeling

Posted: 11/22/02

 

Back to Drug Side Effects


source: FDA


last update: December 2004





This information is not intended to be a substitute for professional medical advice. You should not use this material to diagnose or treat a health condition or disease without consulting with your healthcare provider.
Privacy Policy  © 1998-2017 Personal Health Zone
Click above for Service Agreement and Contact Information. Accessing this service binds you to terms stated. Advertisements appear throughout this website as a means of funding the site. This site is updated monthly and operates independently of any health associations or organizations. The owner of this site has no medical training and the information presented comes from government resources and health professionals in their respected fields.

Home Page: Personal Health Zone
HONcode accreditation seal. We comply with the HONcode standard for trustworthy health information:
verify here.