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Brand Name: Xopenex®
Active Ingredient:   levalbuterol HCl
Strength(s): 0.63mg/3ml & 1.25mg/3ml unit dose vials
Dosage Form(s):   Inhalation solution
Availability:         Prescription only
Company Name:    Sepracor Inc.
*Date Approved by FDA:   March 25, 1999
*Approval by FDA does not mean that the drug is available to consumers at this time.

What is Xopenex used for? Xopenex is used to treat or prevent narrowing of the airways, (bronchospasm), in adults and children 12 years of age and older with reversible obstructive airway disease, e.g., asthma. The safety and effectiveness of Xopenex in children less than 12 years of age has not been established.

Who should not take Xopenex?

You should not take Xopenex if you have had any type of reaction to medicines containing levalbuterol or albuterol.

Special Warnings with Xopenex:

  • Xopenex can produce a narrowing of the airways called paradoxical bronchospasm in some patients, which may be life threatening.
  • Your health care provider may need to prescribe other medications in addition to Xopenex to help control your asthma. Do not stop taking other asthma medications unless advised by your health care provider.
  • Xopenex can cause significant heart-related side effects, such as an increase in pulse, blood pressure, and/or related symptoms. If you have a heart condition, your doctor will determine if Xopenex is right for you.
  • Use as directed by your doctor or health care provider. Deaths have been reported with similar inhaled medications in asthma patients who use too much.
  • Hypersensitivity reaction, (severe allergic reaction) may occur immediately after taking Xopenex. Experiencing itching, areas of skin swelling (angioedema), skin rash, or narrowing of the airways, may be signs of a hypersensitivity reaction.

General Precautions with Xopenex: 

If you currently have, or have a history of the following conditions, your health care provider will evaluate you to decide if Xopenex is right for you:

  • Heart disease, (e.g., reduced heart circulation, high blood pressure, and irregular heartbeat)
  • Seizures
  • High levels of thyroid hormone
  • Diabetes
  • Reactions to medications similar to Xopenex

What should I tell my doctor or health care provider?

Review all medications that you are taking with your health care provider, including those that you take without a prescription. Because of the potential to interact with Xopenex and cause side effects, tell your doctor or health care provider if you are taking other medications such as:

  • Diuretics such as furosemide and hctz
  • Antidepressants such as monoamine oxidase inhibitors or tricyclic antidepressants
  • Drugs known to affect the heart’s regular rhythm
  • Drugs used for high blood pressure or after a heart attack, such as metoprolol or atenolol

Tell your doctor if you are trying to become pregnant, are already pregnant, or are breast-feeding.

What are some possible side effects of Xopenex? (This is NOT a complete list of side effects reported with Xopenex. Your health care provider can discuss with you a more complete list of side effects.)

Side effects of Xopenex may depend on the dose. Xopenex may result in some temporary increase in heart rate, tremor, and nervousness.

For more detailed information about Xopenex, ask your health care provider.    Link to Xopenex's Labeling

Posted 4/20/99
Revised 7/11/01


Back to Drug Side Effects

source: FDA

last update: December 2004

This information is not intended to be a substitute for professional medical advice. You should not use this material to diagnose or treat a health condition or disease without consulting with your healthcare provider.
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