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Ginger Side Effects, Interactions and Warnings



  • Heartburn or stomach distress can occur if taken in large quantities.
    - Murray, M. -- The Pill Book Guide to Natural Medicines: Vitamins, Minerals, Nutritional Supplements, Herbs, and Other Natural Products. -- Bantam, 2002. 664.

  • Ginger reinforces warfarin action by heterogeneous mechanisms. It should thus not be used in patients on oral anticoagulant and/or antiplatelet therapy.
    - Oral anticoagulants and medicinal plants. An emerging interaction -- Argento A, Tiraferri E, Marzaloni M. -- Ann Ital Med Int. 2000 Apr;15(2):139-43.

  • Ginger may increase the risk of bleeding or potentiate the effects of warfarin therapy.
    - Am J Health Syst Pharm 2000 Jul 1;57(13):1221-7; quiz 1228-30 -- Potential interactions between alternative therapies and warfarin. -- Heck AM, DeWitt BA, Lukes AL.

  • This study investigated the effect of ginger, a common morning sickness remedy, on fetal development. Pregnant Sprague-Dawley rats were administered, from gestation day 6 to 15, 20 g/liter or 50 g/liter ginger tea via their drinking water and then sacrificed at day 20. No maternal toxicity was observed, however embryonic loss in the treatment groups was double that of the controls (P<0.05). no="" gross="" morphologic="" malformations="" were="" seen="" in="" the="" treated="" fetuses.="" fetuses="" exposed="" to="" ginger="" tea="" were="" found="" to="" be="" significantly="" heavier="" than="" controls,="" an="" effect="" that="" was="" greater="" in="" female="" fetuses="" and="" was="" not="" correlated="" with="" increased="" placental="" size.="" treated="" fetuses="" also="" had="" more="" advanced="" skeletal="" development="" as="" determined="" by="" measurement="" of="" sternal="" and="" metacarpal="" ossification="" centers.="" the="" results="" of="" this="" study="" suggest="" that="" in="" utero="" exposure="" to="" ginger="" tea="" results="" in="" increased="" early="" embryo="" loss="" with="" increased="" growth="" in="" surviving="">
    - Reprod Toxicol 2000 Nov-Dec;14(6):507-12 -- Effect of ginger tea on the fetal development of Sprague-Dawley rats. -- Wilkinson JM.

  • Ginger may help to lessen nausea due to chemotherapy drugs and anesthesia.
    - Murray, M. -- The Pill Book Guide to Natural Medicines: Vitamins, Minerals, Nutritional Supplements, Herbs, and Other Natural Products. -- Bantam, 2002. 664.








last update: February 2014



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