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Coenzyme Q10 Side Effects, Interactions and Warnings

Coenzyme Q10 has been associated with documented reports of potential interactions with warfarin.
- Am J Health Syst Pharm 2000 Jul 1;57(13):1221-7; quiz 1228-30 -- Potential interactions between alternative therapies and warfarin. -- Heck AM, DeWitt BA, Lukes AL.

Adverse effects with CoQ10 supplementation are rarely reported, but include headache, heartburn, fatigue, and increased involuntary movements at high doses of 600 mg to 1200 mg per day. Mild diarrhea and skin reactions have also been reported.

Adverse reactions to Co-Q10 include anorexia, diarrhea, epigastric discomfort, ischemic tissue damage - tissue damage due to a deficiency in blood in a specific part of the body (during intense exercise), and mild nausea.
- Fetrow CW, Avila JR. Professional's handbook of complementary and alternative medicines. Springhouse, Pennsylvania: Springhouse Corporation 1999:178-80.

This information is not intended to be a substitute for professional medical advice. You should not use this material to diagnose or treat a health condition or disease without consulting with your healthcare provider.
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