Arginine

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Arginine Side Effects, Interactions and Warnings


  • In the studies conducted, arginine deficiency suppressed herpes simplex virus replication in tissue culture. Lysine, an analog of arginine, as an antimetabolite, antagonized the viral growth-promoting action of arginine. The in vitro data may be the basis for the observation that patients prone to herpetic lesions and other related viral infections, particularly during periods of stress, should abstain from arginine excess and may also require supplemental lysine in their diet.
    - Chemotherapy 1981;27(3):209-13 -- Relation of arginine-lysine antagonism to herpes simplex growth in tissue culture. -- Griffith RS, DeLong DC, Nelson JD.

  • A report of the second anaphylactoid reaction to arginine in a child undergoing stimulation testing with arginine for assessing GH secretion.
    - Ann Allergy Asthma Immunol 2002 Jan;88(1):67-8 -- Case report of an anaphylactoid reaction to arginine. -- Resnick DJ, Softness B, Murphy AR, Aranoff GS, Levine LS.

  • High doses of arginine may be toxic and have an effect on one's weight.
    - Br J Nutr 1995 Dec;74(6):787-95 -- High doses of dietary arginine during repletion impair weight gain and increase infectious mortality in protein-malnourished mice. -- Peck MD, Babcock GF, Alexander JW, Billiar T, Ochoa J.




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  • last update: February 2014



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