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White Willow Side Effects, Interactions and Warnings

Upset stomach, nausea, or ringing in the ears may result. Lower the dosage or stop using white willow; call your doctor if symptoms persist.

Children under the age of 16 should not use white willow if they have a cold, influenza, or other viral illness. Using salicylates may cause Reye's syndrome, a potentially fatal condition.
- Ann Pharmacother. 2005 Jul-Aug;39(7-8):1234-7. Epub 2005 May 31. Evaluation of presence of aspirin-related warnings with willow bark. Clauson KA, Santamarina ML, Buettner CM, Cauffield JS.

Individuals with ulcers or other stomach problems should use white willow with caution, because it can worsen stomach ills.

Do not mix white willow with other salicylates, such as aspirin or wintergreen oil, because of the potential for additive side effects.

May interfere with absorption of iron and other minerals when taken internally.

Incidences of hepatotoxicity and nephrotoxicity may be augmented by acetaminophen when concomitantly used with the potentially hepatotoxic herbs Echinacea and kava, and with herbs containing salicylate (willow, meadowsweet), respectively.
- J Clin Pharm Ther 2002 Dec;27(6):391-401 -- Herbal medication: potential for adverse interactions with analgesic drugs. -- Abebe W.

A case of anaphylaxis resulting from the use of a willow bark-containing dietary supplement in a patient with a history of an aspirin allergy. The use of any willow bark-containing dietary supplement may present a risk of anaphylactic reaction to patients with a history of allergy to salicylates.
- Ann Pharmacother. 2003 Jun;37(6):832-5. -- Anaphylactic reaction to a dietary supplement containing willow bark. -- Boullata JI, McDonnell PJ, Oliva CD. CONCLUSIONS:

last update: March 2010

This information is not intended to be a substitute for professional medical advice. You should not use this material to diagnose or treat a health condition or disease without consulting with your healthcare provider.
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